My Prophylactic Salpingectomy with Delayed Oophorectomy (PSDO) – Fallopian Tube Removal for BRCA+ to Decrease Ovarian Cancer Risk
After I had breast cancer, I found out I was BRCA1+. Because of this gene mutation, I have a high risk of getting ovarian cancer. In order to decrease my ovarian cancer risk, I had surgery to remove my fallopian tubes.
Here is my video, Fallopian Tube Removal Surgery for BRCA+ Ovarian Cancer Risk Reduction – Laparoscopic Prophylactic Salpingectomy with Delayed Oophorectomy (PSDO).
BRCA Gene Mutation: Decreasing Ovarian Cancer Risk with Fallopian Tube Removal – Prophylactic Salpingectomy with Delayed Oophorectomy (PSDO)
Breast Cancer Diagnosis and BRCA Testing
After my 2009 diagnosis of breast cancer, I took the BRCA test. BRCA is a gene mutation that increases one’s risk of breast and ovarian cancers. Not surprisingly, I tested positive for BRCA1 187 del AG which results in a stop codon at amino acid 39 of the BRCA1 protein. In other words, my risk of getting breast cancer or ovarian cancer is a lot higher than the general population.
Since I have already had a bilateral mastectomy and chemotherapy for breast cancer, there is not much more I can do to reduce my risk of breast cancer. The next step is to focus on reducing my risk of ovarian cancer.
BRCA and Increased Ovarian Cancer Risk
Unfortunately, there are no effective methods of screening for ovarian cancer. When ovarian cancer is detected, it has often spread to other parts of the body. Currently, there are various options for BRCA+ women in terms of surveillance and risk reduction. Although not always effective, women may choose to have the tumor marker CA125 checked and ultrasounds performed every 6 months.
Oopherectomy (removal of ovaries) is the most effective way to decrease ovarian cancer risk. Many doctors recommend oophorectomy around age 4o. Unfortunately, bilateral oophorectomy before natural menopause is associated with several negative outcomes such as cardiovascular disease, cognitive impairment, bone issues, emotional and sexual problems, and increased risk of premature death. That sounds pretty scary, right?
Ovarian Cancer May Start in Fallopian Tubes
Recently, there is research suggesting ovarian cancer may start in the fallopian tubes. Now, because of this theory, doctors are starting to recommend salpingectomy (fallopian tube removal) for ovarian cancer prevention in premenopausal women.
As a result of this theory, a study at M.D. Anderson Cancer Center, Prophylactic Salpingectomy With Delayed Oophorectomy is currently recruiting participants. The goal of this clinical research study is to compare ovarian cancer screening, risk-reducing salpingo-oophorectomy (RRSO), and prophylactic salpingectomy with delayed oophorectomy (PSDO).
After lots of discussions and my own research, I chose to participate in this fallopian tube removal option for BRCA+ women. For me, I felt like my body was a ticking time bomb. At the age of 37, I was having a hard time waiting around until age 40+ to reduce my risk of ovarian cancer. I was also not ready to face the issues associated with surgical menopause.
My Laparoscopic Prophylactic Salpingectomy with Delayed Oophorectomy (PSDO)
On September 14, my husband and I arrived in Houston for pre-op appointments and testing. Thankfully, everything came back normal and my surgery was confirmed for the next day.

On September 15, 2015, we arrived at MD Anderson at 6:30 am for an 8:30 am surgery. Then, we waited a long time in the waiting room. Finally, they gave me a room. First, they inserted the IV. They gave me a scopolamine transdermal patch behind my ear to prevent nausea. By the time they wheeled me out and gave me the happy drugs it was about 9:15 am or so.
Recovery After My Fallopian Tubes Were Removed
The laparoscopic salpingectomy itself went well, but there was a complication during surgery. For some reason, perhaps due to IBS, my small intestine swelled during surgery. To be sure there were no punctures, both my doctor and a gastroenterologist spent a lot of time checking my whole small intestine. After a long time of pulling and stretching the doctor found no injuries. The surgery was supposed to last only 1.5 hours, but because of the intestinal problems, my surgery lasted 3 hours.
Normally, a laparoscopic salpingectomy is an outpatient procedure, but because of the intestinal complication, I had to spend the night at the hospital. This was because my doctor wanted to monitor me overnight to make sure I had no intestinal complications.
Pain after the laparoscopic salpingectomy for ovarian cancer risk reduction
After surgery, the pain was not too bad. On a scale of 0-10, the pain was around a 3. My stomach was bloated and gassy since they add a lot of air to the abdomen to improve surgical visibility. I was warned before surgery to expect to have a lot of gas after surgery. There’s only one way to get it out.
The most annoying part of recovery were side effects of either anesthesia or the scopolamine patch. Somehow, no one thought to remove my patch right after surgery as recommended. The patch remained on for a few days until I complained to my doctor the day we were going back to Austin.
My vision was blurry, especially up close. In addition, I had a hard time reading, texting, etc. for almost a week. For a while, I felt nauseous, lightheaded, and dizzy.
Recovery from laparoscopic salpingectomy
Finally, I’m feeling almost back to normal. I was able to drive today. The lightheadedness is gone, but I am still weak and little nauseous.
I do have some post-surgery restrictions for the next few weeks. After 4 weeks, I can resume running. After 6 weeks, I can start lifting more than 10 pounds and go back to doing abdominal exercises and Pilates.
I will come back and update this post and let you know how I am recovering.
Pictures of laparoscopic salpingectomy after surgery
Here are some pictures of my stomach now with the steristrips. You’ll see there are 4 incisions. Normally, with laparoscopic salpingectomy, there are 3 incisions – 2 for fallopian tube removal and one for the camera. Since I had intestinal issues, the surgeon made another incision to check my bowels/ small intestine.
4 days after My Laparoscopic Prophylactic Salpingectomy Fallopian Tube Removal to Reduce Ovarian Cancer Risk
8 days after surgery – laparoscopic salpingectomy
Learn more about salpingectomy for ovarian cancer risk reduction
If you would like to learn more about salpingectomy as a way to reduce ovarian cancer risk for BRCA+ women, then here are some articles.
- Salpingectomy for Ovarian Cancer Prevention
- Intercepting pelvic cancer in the distal fallopian tube: Theories and realities
- Opportunistic and interventional salpingectomy in women at risk: a strategy for preventing pelvic serous cancer (PSC)
- Prophylactic oophorectomy in pre-menopausal women and long term health – a review
- Primary Fallopian Tube Malignancies in BRCA-Positive Women Undergoing Surgery for Ovarian Cancer Risk Reduction
Read more about my breast cancer journey from 2009 to the present here. If you know anyone having a mastectomy or other breast surgery, these breast cancer recovery shirts are a must-have.
Such a brave soul…fight the good fight (’nuff respect)!
I found your video by accident while researching BRCA options. I’m BRCA 2 and struggling with preventative surgery recommendations. Thanks so much for posting this and the link to the clinical trial. I am not ready to give up my ovaries yet, even though I’m in my later 40’s, because I have not started menopause. A salpingectomy may be my better option for the time being. So far my issue has been getting an oncologist to agree to it.
Thanks for commenting. I’m glad you found my video. I hope you are able to find someone to do a salpingectomy. What city are you in?
Hi Rachel,
I really appreciated this video clip! It was really helpful and reassuring before I had my salpingectomy last year at age 38. I was wondering if you have an e-mail address that I could contact you privately? I am happy with my choice. I wasn’t able to be involved in any clinical trials since there are none near where I live. Personal risk to age 50 is 2% so with this procedure and birth control use for numerous years, I feel my risk is near the general population up to this age and then I plan to revisit around that age. I am very hopeful based on my own research so far that tube removal does in fact provide a significant risk reduction hopefully near BSO.
Hi Rachel, I am BRCA2+ and have had a double mastectomy with diep flap reconstruction. I am in the process of researching my options to reduce ovarian cancer risk, and like you I decided to go with salpingectomy with delayed oophorectomy. Your post was 2 years ago, how are things with you now? When are you planning your oophorectomy and are you happy with your decision?